Xalatan versus xalacom12/8/2022 ![]() ![]() Three quantitative techniques are used to merge the results of studies 2 and 3 in order to determine which technique best approximates the gold standard double-blinded RCT results. The third study is an observational study comparing Xalacom to a placebo. The second study is a single-blinded RCT comparing Xalatan to a placebo. The first is a double-blinded RCT comparing the difference in lowering intraocular pressure between the anti-glaucoma medications Xalatan and Xalacom. Three different clinical studies are evaluated. This work assesses that question directly. Observational data is more readily available, however it is not oftentimes clear how comparable the findings are between observational and RCT data. However, obtaining RCT data is time-consuming and expensive. ![]() Randomized controlled trials (RCTs) are a standard for assessing the benefit of competing healthcare interventions. ![]()
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